{"id":1004,"date":"2016-09-13T14:40:43","date_gmt":"2016-09-13T14:40:43","guid":{"rendered":"http:\/\/doktermuslim.com\/?p=1004"},"modified":"2016-09-13T14:40:43","modified_gmt":"2016-09-13T14:40:43","slug":"liken-simpleks-kronis-lsk","status":"publish","type":"post","link":"https:\/\/doktermuslim.com\/liken-simpleks-kronis-lsk\/","title":{"rendered":"Liken simpleks kronis (LSK)"},"content":{"rendered":"

DEFINISI<\/u><\/strong><\/h3>\n

Lichen Simpleks Kronis (LSK) adalah reaksi radang pada kulit, kronis, gatal, sirkumskripta, dan ditandai dengan kulit yang menebal (Likenifikasi), mirip dengan kayu kasar dengan bekas garukan. Nama lain dari Liken simpleks kronis (LSK) adalah neurodermatitis.<\/p>\n

Jarang teradi pada anak, sering pada orang tua usia 40-50 tahun. Letak lesi di mana saja, seperti tengkuk, lutut, pubis, ekstensor, tungkai dan wanita lebih sering menderita dibanding pria.<\/p>\n

\n

ETIOLOGI<\/u><\/strong><\/h3>\n

Penyebab dari LSK di kaitkan dengan beberapa penyakit seperti gagal ginjal kronis, obstruksi saluran empedu, lomfoma Hodgkin, hipertiroid, dermatitis atopic, dermatitis kontak alergi, gigitan serangga, dan stress emotional.<\/p>\n

\n

TANDA DAN GEJALA<\/u><\/strong><\/h3>\n

Pada Liken simpleks kronis, pasien akan merasakan gatal pada daerah dengan LSK terutama saat malam hari. Gatal tidak bersifat terus menerus, tetapi intens. Gatal yang muncul, sangat memicu penderita untuk menggaruknya.<\/p>\n

Garukan akan membuat rangsang nyeri, sehingga rasa gatal mereda tetapi ini akan menimbulkan luka bekas garukan.<\/p>\n

Lesi bersifat tnggal, berupa plak eritematosa, dengan menebal dan berskuama, terjadi likenifikasi dan terdapat ekskoriasi dengan tepi hiperpigmentasi dan batas tidak jelas.<\/p>\n

\n

HISTOPATOLOGIS<\/u><\/strong><\/h3>\n

Pada pemeriksaan histopatologis akan didapatkan hipergranulosis, ortokeratosis, akantosis dengan rete ridges memanjang teratur.\u00a0 Dikelilingi sel radang, fibroblast, kolagen menebal, sel schwan proliferasi, terlihat hiperplasi. Beberapa kasus ditemukan krusta di superficial epidermis.<\/p>\n

\n

DIAGNOSIS<\/u><\/strong><\/h3>\n

Untuk menegakkan diagnosis dari LSK, hanya perlu gambaran klinis dan gejala yang dialami pasien. Pertimbangkan juga diagnosis lain seperti, dermatitis atopic, psoriasis. Gali riwayat alergi, riwayat pengobatan.<\/p>\n

\n

TATALAKSANA<\/u><\/strong><\/h3>\n

Tatalaksana dari LSK adalah :<\/p>\n\n\n\n\n\n\n
Berikan antipruritus berupa antihistamin (seperti difenhidramin, prometazin, hidroksizin)<\/td>\n<\/tr>\n
Dapat diberikan topical krim doxapin 5% maksimal 8 hari<\/td>\n<\/tr>\n
Steroid dapat digunakan dengan steroid yang paling potent seperti klobetason.<\/td>\n<\/tr>\n
Salep steroid kadang dikombinasikan dengan TER<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\n

REFERENSI<\/u><\/strong><\/h3>\n

Harting M, dkk. Dermal hypertrophies. Dalam: Wolff K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ,editor. Fitzpatrick\u2019s Dermatology in General Medicine.<\/strong> <\/em>Edisi ke-7. New York: McGraw-Hill; 2008. h.550-6<\/p>\n","protected":false},"excerpt":{"rendered":"

DEFINISI Lichen Simpleks Kronis (LSK) adalah reaksi radang pada kulit, kronis, gatal, sirkumskripta, dan ditandai dengan kulit yang menebal (Likenifikasi), mirip dengan kayu kasar dengan [Read more]<\/a><\/p>\n","protected":false},"author":1,"featured_media":1005,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[28,31],"tags":[199,200,198,196],"newstopic":[],"yoast_head":"\nLiken simpleks kronis (LSK) | Dokter Muslim<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/doktermuslim.com\/liken-simpleks-kronis-lsk\/\" \/>\n<meta property=\"og:locale\" content=\"id_ID\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Liken simpleks kronis (LSK) | Dokter Muslim\" \/>\n<meta property=\"og:description\" content=\"DEFINISI Lichen Simpleks Kronis (LSK) adalah reaksi radang pada kulit, kronis, gatal, sirkumskripta, dan ditandai dengan kulit yang menebal (Likenifikasi), mirip dengan kayu kasar dengan [Read more]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/doktermuslim.com\/liken-simpleks-kronis-lsk\/\" \/>\n<meta property=\"og:site_name\" content=\"Dokter Muslim\" \/>\n<meta property=\"article:author\" content=\"https:\/\/www.facebook.com\/doktermuslimcom\/\" \/>\n<meta property=\"article:published_time\" content=\"2016-09-13T14:40:43+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/doktermuslim.com\/wp-content\/uploads\/2016\/09\/LSK.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1300\" \/>\n\t<meta property=\"og:image:height\" content=\"750\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"dr. 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